GO:0031080 cellular_component nuclear pore outer ring
| PAG Title | GO:0031080 cellular_component nuclear pore outer ring |
| PAG ID | TAX020795 |
| Type | A |
| Source Link |  GOA |
| Publication Reference | NA |
| PAG Description | A subcomplex of the nuclear pore complex (NPC) that forms the outer rings of the core scaffold, a lattice-like structure that gives the NPC its shape and strength. In S. cerevisiae, the two outer rings each contain multiple copies of the following proteins: Nup133p, Nup120p, Nup145Cp, Nup85p, Nup84p, Seh1p, and Sec13p. In vertebrates, the two outer rings each contain multiple copies of the following proteins: Nup133, Nup160, Nup96, Nup75, Nup107, Seh1, Sec13, Nup43, Nup37, and ALADIN. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. A single 'spoke', can be isolated and is sometimes referred to as the Nup84 complex (S. cerevisiae) or the Nup107-160 complex (vertebrates). |
| Species | Homo sapiens |
| Quality Metric Scores | nCoCo Score: 4,303 |
| Information Content | Rich |
| Other IDs | GO:0031080 |
| Base PAG ID | TAX020795 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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